RR601 Irritancy and sensitisation
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منابع مشابه
Norfloxacin loaded pH triggered nanoparticulate in situ gel for extraocular bacterial infections: Optimization, ocular irritancy and corneal toxicity
In order to achieve prolong corneal contact time of norfloxacin(NFX) for treatment of extra ocular diseases, a pH triggered nanoparticulate in situ gelling system was designed to explore dual advantage of nanoparticles and in situ gelling system, for its ocular delivery. NFX loaded nanocarriers were developed by ionotropic gelation technique using chitosan as a matrix forming polymer, cross-lin...
متن کاملNorfloxacin loaded pH triggered nanoparticulate in situ gel for extraocular bacterial infections: Optimization, ocular irritancy and corneal toxicity
In order to achieve prolong corneal contact time of norfloxacin(NFX) for treatment of extra ocular diseases, a pH triggered nanoparticulate in situ gelling system was designed to explore dual advantage of nanoparticles and in situ gelling system, for its ocular delivery. NFX loaded nanocarriers were developed by ionotropic gelation technique using chitosan as a matrix forming polymer, cross-lin...
متن کاملAssessment of the in vitro skin irritation of chemicals using the Vitrolife-SkinTM human skin model
Currently, the European Centre for the Validation of Alternative Methods (ECVAM) has supported formal validation studies on in vitro tests for predicting skin irritancy and corrosivity, which included three of the in vitro tests employed human skin models, EPISKINTM and EpiDermTM. When skin models are used to evaluate skin irritancy and corrosivity, it is important that suitable chemical applic...
متن کاملSelected Abstracts of the First World Congress on Work-Related and Environmental Allergy (1st WOREAL)
9–12 July 2003 Helsinki, Finland Exog Dermatol 2003;2:70–112 DOI:10.1159/000074109 Basel · Freiburg · Paris · London · New York · Bangalore · Bangkok · Singapore · Tokyo · Sydney D ow nl oa de d by : 54 .1 91 .4 0. 80 9 /1 7/ 20 17 2 :1 4: 57 P M Symposium 1: Prediction of Irritancy In vivo Irritation Models: Beyond Bioengineering Techniques – New Non-Invasive Approaches Fluhr, J. . . . . . . ....
متن کاملDose-response Evaluation Using an Epidermal Model, an Alternative to Skin Irritation Testing
Using 3-dimensional cultured human skin and epidermal models, an alternative to skin irritation testing have been developed. In the ECVAM (European Centre for the Validation of Alternative Methods) validation protocol, hazardous chemicals have been identified using these models. We considered it likely that these models would also be useful for examining the dose-response of the toxicity of a c...
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تاریخ انتشار 2007